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As each phenol group contains only a single t-butyl group they are considered to have low steric hindrance and thus high activity. Arranging three of these around an isocyanurate core gives a compound with a sufficiently high boiling point that it is not volatilised out of the plastic during plastic extrusion and moulding (up to 320 °C in the case of PA).
Tris(3,5-di-tert-butyl-4-hydroxybenzyl) isocyanurate is a chemical compound used as a polymer stabilizer in plastics. Like other hindered phenols it acts as a primary antioxidant. More than 1000 tonnes per year are used in the EU.
Octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate is significantly less volatile than simpler phenolic antioxidants such as butylhydroxytoluene (BHT). This makes it more suitable to stabilising plastics, as it is not driven out by the high temperatures experienced during plastic extrusion and moulding, [2] when they are heated to 150-320 °C (300–600 °F). [3]
Octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate - an inexpensive and commonly used polymer stabiliser; Tris(3,5-di-tert-butyl-4-hydroxybenzyl) isocyanurate - a polymer stabiliser commonly used to protect against long term heat aging; Irganox 1098 - a polymer stabiliser with metal chelation properties
4-tert-Butylcatechol (TBC) is an organic chemical compound which is a derivative of catechol. [1] TBC is available in the form of a solid crystal flake [ 2 ] and 85% solution in methanol [ 3 ] or water.
Probucol, sold under the trade name Lorelco among others, is an anti-hyperlipidemic drug [1] initially developed for the treatment of coronary artery disease.Clinical use was discontinued in some countries after it was found that the drug may have the undesired effect of lowering HDL in patients with a previous history of heart disease.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
2 Adverse effects. 3 Interactions. 4 Synthesis. 5 References. Toggle the table of contents. ... Treatment with N-(tert-Butyl)benzylamine [3378-72-1] (5) afforded ...
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