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  2. Thrombophilia - Wikipedia

    en.wikipedia.org/wiki/Thrombophilia

    Thrombophilia (sometimes called hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels). [ 1 ] [ 2 ] Such abnormalities can be identified in 50% of people who have an episode of thrombosis (such as deep vein thrombosis in the leg) that was not ...

  3. Hereditary hemorrhagic telangiectasia - Wikipedia

    en.wikipedia.org/wiki/Hereditary_hemorrhagic_tel...

    Hereditary hemorrhagic telangiectasia (HHT), also known as Osler–Weber–Rendu disease and Osler–Weber–Rendu syndrome, is a rare autosomal dominant genetic disorder that leads to abnormal blood vessel formation in the skin, mucous membranes, and often in organs such as the lungs, liver, and brain.

  4. Gene therapy for blood diseases - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy_for_blood...

    The genetically modified T-cells are administered back to the patients as a treatment. Leukemia is a group of blood cancers commonly found in children younger than 15 and elders older than 55. [ 3 ] In 2017, tisagenlecleucel (Kymriah™) , [ 2 ] the first CAR-T cell therapy approved by the FDA , became available to anyone up to the age of 25 ...

  5. How genomic testing can personalize treatment for 150K ... - AOL

    www.aol.com/genomic-testing-personalize...

    Rosalind Brown had blood clots in her lungs. For years, her doctors tried to get the dose of a blood thinner just right to prevent the risk of a heart attack or other life-threatening ...

  6. Pulmonary embolism - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_embolism

    PE usually results from a blood clot in the leg that travels to the lung. [6] The risk of blood clots is increased by advanced age, cancer, prolonged bed rest and immobilization, smoking, stroke, long-haul travel over 4 hours, certain genetic conditions, estrogen-based medication, pregnancy, obesity, trauma or bone fracture, and after some ...

  7. Factor V Leiden - Wikipedia

    en.wikipedia.org/wiki/Factor_V_Leiden

    If the venous clots break off, these clots can travel through the right side of the heart to the lung where they block a pulmonary blood vessel and cause a pulmonary embolism. It is extremely rare for this disorder to cause the formation of clots in arteries that can lead to stroke or heart attack , though a "mini-stroke", known as a transient ...

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