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2. Early goal-directed therapy - Wikipedia

   en.wikipedia.org/wiki/Early_goal-directed_therapy

   Early goal-directed therapy is a more specific form of therapy used for the treatment of severe sepsis and septic shock. This approach involves adjustments of cardiac preload, afterload, and contractility to balance oxygen delivery with an increased oxygen demand before surgery.

3. Surviving Sepsis Campaign - Wikipedia

   en.wikipedia.org/wiki/Surviving_Sepsis_Campaign

   For every hour a patient is denied AB therapy after the onset of septic shock, the patient's chance of survival is reduced by 7.9% (Survivesepsis.org 2005). The 2012 guidelines differ: Administration of broad-spectrum antimicrobials therapy within 1 hr of recognition of septic shock (1B) and severe sepsis without septic shock. [7]

4. Critical illness–related corticosteroid insufficiency - Wikipedia

   en.wikipedia.org/wiki/Critical_illness–related...

   The Surviving Sepsis Campaign guidelines advocate intravenous hydrocortisone only in adults with septic shock and refractory hypotension. [4] The exact definition of this condition, the best ways to test for corticoid insufficiency in critically ill patients, and the therapeutic use of (usually low doses) of corticosteroids remains a subject of ...

5. Septic shock - Wikipedia

   en.wikipedia.org/wiki/Septic_shock

   Septic shock is a result of a systemic response to infection or multiple infectious causes. The precipitating infections that may lead to septic shock if severe enough include but are not limited to appendicitis, pneumonia, bacteremia, diverticulitis, pyelonephritis, meningitis, pancreatitis, necrotizing fasciitis, MRSA and mesenteric ischemia.

6. Multiple organ dysfunction syndrome - Wikipedia

   en.wikipedia.org/wiki/Multiple_organ_dysfunction...

   In patients with sepsis, septic shock, or multiple organ dysfunction syndrome that is due to major trauma, the rs1800625 polymorphism is a functional single nucleotide polymorphism, a part of the receptor for advanced glycation end products (RAGE) transmembrane receptor gene (of the immunoglobulin superfamily) and confers host susceptibility to ...

7. Ashley Park's survival of septic shock offers important lessons

   www.aol.com/ashley-parks-survival-septic-shock...

   In the U.S., there are more than 350,000 deaths per year due to sepsis. Ashley Park's recent septic shock offers important lessons.

8. Drotrecogin alfa - Wikipedia

   en.wikipedia.org/wiki/Drotrecogin_alfa

   Drotrecogin alfa (activated) (Xigris, marketed by Eli Lilly and Company) is a recombinant form of human activated protein C that has anti-thrombotic, anti-inflammatory, and profibrinolytic properties. Drotrecogin alpha (activated) belongs to the class of serine proteases. Drotrecogin alfa has not been found to improve outcomes in people with ...

9. Sepsis - Wikipedia

   en.wikipedia.org/wiki/Sepsis

   10 to 80% risk of death; [4] [6] These mortality rates (they are for a range of conditions along a spectrum: sepsis, severe sepsis, and septic shock) may be lower if treated aggressively and early, depending on the organism and disease, the patient's previous health, and the abilities of the treatment location and its staff: Frequency