Search results
Results from the WOW.Com Content Network
In enzymology, a 5-oxoprolinase (ATP-hydrolysing) (EC 3.5.2.9) is an enzyme that catalyzes the chemical reaction. ATP + 5-oxo-L-proline + 2 H 2 O ADP + phosphate + L-glutamate. The 3 substrates of this enzyme are ATP, 5-oxo-L-proline, and H 2 O, whereas its 3 products are ADP, phosphate, and L-glutamate.
The names of pyroglutamic acid conjugate base, anion, salts, and esters are pyroglutamate, 5-oxoprolinate, or pidolate. Formation of pyroglutamic acid from N-terminal glutamine. It is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase. Pyroglutamate is found in many proteins including bacteriorhodopsin.
The conversion of the amino acid glutamine to α-ketoglutarate takes place in two reaction steps: Conversion of glutamine to α-ketoglutarate. 1. Hydrolysis of the amino group of glutamine yielding glutamate and ammonium. Catalyzing enzyme: glutaminase (EC 3.5.1.2) 2. Glutamate can be excreted or can be further metabolized to α-ketoglutarate.
The enzyme catalyzes the reaction above, an important step in the synthesis of phenylalanine, tyrosine, and tryptophan. From left to right, the species involved are L-arogenate, 2-oxoglutarate, prephenate, and L-glutamate., and its primary purpose is to convert prephenate into arogenate via transamination, using glutamate as the amino donor.
Arginine and proline metabolism is one of the central pathways for the biosynthesis of the amino acids arginine and proline from glutamate. The pathways linking arginine, glutamate, and proline are bidirectional. Thus, the net utilization or production of these amino acids is highly dependent on cell type and developmental stage.
WASHINGTON (Reuters) -A lead prosecutor on the criminal case accusing Donald Trump of illegally holding onto classified documents has left the U.S. Justice Department ahead of the president-elect ...
The end product of the glutaminase reaction, glutamate, is a strong inhibitor of the reaction. Changes in glutamate dehydrogenase, which converts glutamate to 2-oxoglutarate and thereby decreases intramitochondrial glutamate levels, are thereby an important regulatory mechanism of glutaminase activity.
AirTags are incredible—they keep you from losing your important things (like keys, wallets, and even phones). And today, you can score your own four-pack for a jaw-dropping 30% discount.