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Myoclonus may also develop in response to infection, hyperosmolar hyperglycemic state, head or spinal cord injury, stroke, stress, brain tumors, kidney or liver failure, lipid storage disease, chemical or drug poisoning, as a side effect of certain drugs (such as tramadol, [6] quinolones, benzodiazepine, gabapentin, sertraline, lamotrigine ...
Tardive myoclonus, a rare disorder, presents as brief jerks of muscles in the face, neck, trunk, and extremities. [13] "AIMS Examination": This test is used when psychotropic medications have been prescribed because people sometimes develop tardive dyskinesia due to prolonged use of antipsychotic medications.
These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Chorea may also be caused by drugs (commonly levodopa, anti-convulsants and anti-psychotics). [ 2 ] Other acquired causes include CSF leak , [ 3 ] systemic lupus erythematosus , antiphospholipid syndrome , thyrotoxicosis , polycythaemia rubra vera , [ 2 ] transmissible spongiform encephalopathies , coeliac disease [ 4 ] and gluten ataxia .
Myoclonic dystonia or Myoclonus dystonia syndrome is a rare movement disorder that induces spontaneous muscle contraction causing abnormal posture. The prevalence of myoclonus dystonia has not been reported, however, this disorder falls under the umbrella of movement disorders which affect thousands worldwide. [1]
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
Causes painful defecation, constipation; may be complicated by encopresis or fecal incontinence. Cervical dystonia (spasmodic torticollis) muscles of the neck: Causes the head to rotate to one side, to pull down towards the chest, or back, or a combination of these postures. Blepharospasm: muscles around the eyes
Treatment was based on the theory that there is an imbalance of the neurotransmitter dopamine in the basal ganglia. These drugs have fallen out of fashion due to various serious side effects: sedation, parkinsonism, and tardive dyskinesia. [16] Other oral medications can be used in low doses to treat early stages of spasmodic torticollis.