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Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. [10] This includes middle ear infections, strep throat, pneumonia, traveler's diarrhea, and certain other intestinal infections. [10]
AUC it is a measure of the drug exposure in the body over time. By inhibiting CYP3A4, macrolide antibitiotics, such as erythromycin and clarithromycin, but not azithromycin, can significantly increase the AUC of the drugs that depend on it for clearance, which can lead to higher risk of adverse effects or drug-drug interactions. Azithromycin ...
Fluoroquinolone antibiotics can be life-saving drugs when used against specific bacteria - and serious side effects are considered rare. ... for urinary tract infections, for prophylaxis (to ...
Those can include alcohol, tea and coffee, which have diuretic effects and irritate the bladder, said Dr. David Shusterman, a board-certified urologist at NY Urology in New York City ...
Gram-positive organisms, but is inhibited by pulmonary surfactant so less effective against pneumonias: Binds to the membrane and cause rapid depolarization, resulting in a loss of membrane potential leading to inhibition of protein, DNA and RNA synthesis. Macrolides(Bs) Azithromycin: Zithromax, Sumamed, Xithrone
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