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The expansion, titled NoxQuest, was released as a free download on August 1, 2000, and focused on the multiplayer aspects of the game. [ 34 ] [ 35 ] It included the last patch , updating the game to version 1.2, and featured a number of new spells invented for but not implemented in the original game.
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YouTube was founded on 15 February 2005 and is now the leading website for free streaming video with more than two billion users. [93] It uses an HTML5 based web player by default to stream and show video files. [94] Registered users may upload an unlimited amount of video and build their own personal profile.
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Arthropods have three NOX types (NOX4-art, an arthropod-specific p22-phox-independent NOX4, and two calcium-dependent enzymes, DUOX). [ 16 ] [ 17 ] [ 18 ] In the gut, DUOX-dependent ROS production from bacteria-stimulated Drosophila melanogaster mucosa is an important pathogen-killing mechanism [ 19 ] and can increase defecation as a defense ...
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