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Toxic shock syndrome (TSS) is a condition caused by bacterial toxins. [1] Symptoms may include fever , rash , skin peeling , and low blood pressure . [ 1 ] There may also be symptoms related to the specific underlying infection such as mastitis , osteomyelitis , necrotising fasciitis , or pneumonia .
Toxic shock syndrome toxin-1 (TSST-1) is a superantigen with a size of 22 kDa [1] produced by 5 to 25% of Staphylococcus aureus isolates. It causes toxic shock syndrome (TSS) by stimulating the release of large amounts of interleukin-1, interleukin-2 and tumor necrosis factor. In general, the toxin is not produced by bacteria growing in the ...
Nikolsky's sign is almost always present in Stevens–Johnson syndrome/toxic epidermal necrolysis [5] and staphylococcal scalded skin syndrome, caused by the exfoliative toxin of Staphylococcus aureus. [1] It is also associated with pemphigus vulgaris and pemphigus foliaceus.
Unlike a heat rash (which is often caused by irritation), other rashes are sparked by allergic reactions, like contact dermatitis. This itchy rash is caused by direct contact with a substance that ...
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Toxic shock syndrome is characterized by fever, erythematous rash, low blood pressure, shock, multiple organ failure, and skin peeling. Lack of antibody to TSST-1 plays a part in the pathogenesis of TSS. Other strains of S. aureus can produce an enterotoxin that is the causative agent of a type of gastroenteritis. This form of gastroenteritis ...
An 8-year-old Colorado girl's suspected food allergy turned out to be a life-threatening diagnosis that is often linked to the use of tampons.