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2. Hepatotoxicity - Wikipedia

   en.wikipedia.org/wiki/Hepatotoxicity

   Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents.

3. Hy's law - Wikipedia

   en.wikipedia.org/wiki/Hy's_law

   Hy's law is a rule of thumb that a patient is at high risk of a fatal drug-induced liver injury if given a medication that causes hepatocellular injury (not Hepatobiliary injury) with jaundice. [1] The law is based on observations by Hy Zimmerman, a major scholar of drug-induced liver injury.

4. Paracetamol poisoning - Wikipedia

   en.wikipedia.org/wiki/Paracetamol_poisoning

   Other forms of liver support have been used including partial liver transplants. These techniques have the advantage of supporting the patient while their own liver regenerates. Once liver function returns immunosuppressive drugs are commenced and they have to take immunosuppressive medication for the rest of their lives. [86] [87]

5. FDA places its most serious warning on menopause drug due to ...

   www.aol.com/news/fda-places-most-serious-warning...

   The FDA first warned in September that the drug could cause liver problems. It escalated that warning after reviewing the case of a person with blood markers of liver injury who had been taking ...

6. Liver disease - Wikipedia

   en.wikipedia.org/wiki/Liver_disease

   Analogous terms such as "drug-induced" or "toxic" liver disease are also used to refer to disorders caused by various drugs. [ 7 ] Fatty liver disease (hepatic steatosis ) is a reversible condition where large vacuoles of triglyceride fat accumulate in liver cells. [ 8 ]

7. Pharmacotoxicology - Wikipedia

   en.wikipedia.org/wiki/Pharmacotoxicology

   This type of adverse effect that results from pharmaceutical drug exposure is commonly due to interactions of the drug with its intended target. In this case, both the therapeutic and toxic targets are the same. To avoid toxicity during treatment, many times the drug needs to be changed to target a different aspect of the illness or symptoms.

8. Akero's fatty liver disease drug lessens scarring in mid ...

   www.aol.com/news/akeros-lead-drug-helps-reduce...

   (Reuters) -Akero Therapeutics' experimental drug for a type of fatty liver disease significantly reduced scarring after nearly two years in a mid-stage study, it said on Monday, as the company ...

9. Side effects of bicalutamide - Wikipedia

   en.wikipedia.org/wiki/Side_effects_of_bicalutamide

   [155] [156] [157] Rates of abnormal liver function tests have varied widely between studies, with reported ranges of 4 to 62% with flutamide and 2 to 33% with nilutamide. [123] [158] [159] The risk of serious or fatal liver toxicity with flutamide has been estimated to be 3 in 10,000 cases, and other studies suggest an even higher incidence.