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A systematic review showed that there is a strong co-relation between HbA1c values and Vibration Perception Test and could be a predictor for complications in the foot following Diabetic Peripheral Neuropathy. [4]
In some instances, other health conditions cause this disorder. Diabetes mellitus and impaired glucose tolerance are the most common diseases that lead to this disorder, with 6 to 50 percent of diabetics or pre-diabetics developing small fiber neuropathy.
In people with diabetic peripheral neuropathy, two reviews make a case for nerve decompression surgery as an effective means of pain relief and support claims for protection from foot ulceration. [114] [115] There is less evidence for efficacy of surgery for non-diabetic peripheral neuropathy of the legs and feet. One uncontrolled study that ...
One being immobilization, by placing the foot in a neutral position with a brace, pressure is relieved from the tibial nerve thus reducing patients pain. [ 13 ] [ 14 ] [ 15 ] Eversion , inversion , and plantarflexion all can cause compression of the tibial nerve therefore in the neutral position the tibial nerve is less agitated.
Additionally, BP control in those with diabetes is helpful, while intravenous immunoglobulin is used for multifocal motor neuropathy. [1] According to Lopate, et al., methylprednisolone is a viable treatment for chronic inflammatory demyelinative polyneuropathy (which can also be treated with intravenous immunoglobulin).
There is some limited evidence that ALA is also helpful in some other non-diabetic neuropathies. [75] Benfotiamine is an oral prodrug of Vitamin B1 that has several placebo-controlled double-blind trials proving efficacy in treating neuropathy and various other diabetic comorbidities. [76] [77]
Sensory neuronopathy differs from the more common length dependent axonal polyneuropathies (such as diabetic sensorimotor polyneuropathy) in that the symptoms do not progress in a distal to proximal pattern (starting in the feet and progressing to the legs and hands), rather symptoms develop in a multifocal, asymmetric, and non-length dependent ...
Vasculitic neuropathy is a peripheral neuropathic disease. [1] [2] [3] In a vasculitic neuropathy there is damage to the vessels that supply blood to the nerves.[1] [2] [3] It can be as part of a systemic problem or can exist as a single-organ issue only affecting the peripheral nervous system (PNS).