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Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
Benzodiazepines act as a central nervous system depressant. The relative strength of each of these properties in any given benzodiazepine varies greatly and influences the indications for which it is prescribed. Long-term use can be problematic due to the development of tolerance to the anticonvulsant effects and dependency.
Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
If they’re stored in optimal conditions, you can get the most bang for your buck. Best case scenario, the average shelf-life of vitamins is two years, Davis-Cadogan adds. There are some vitamins ...
It opened early, for one day, on April 27, to entertain those preparing to evacuate the northern Ukrainian city. Michał Dziekański / 500px Prime / Getty Images CC Pripyat, Ukraine: After
The roof hasn't been opened for a Cowboys game in their $1.2 billion stadium since the 2022 season. “I know we opened it long before any fans or anybody is in there,” owner Jerry Jones said ...
Ethoxzolamide, a sulfonamide, inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. It also decreases carbonic anhydrase in the CNS, increasing the seizure threshold.
When you're a kid, there's really no time early enough to open your presents on Christmas morning. But it turns out that opening your presents before breakfast apparently makes you seem "vulgar ...
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