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An oncocytoma is a tumor made up of oncocytes, epithelial cells characterized by an excessive amount of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. [ 1 ] [ 2 ] The cells and the tumor that they compose are often benign but sometimes may be premalignant or malignant .
Gross appearance of a renal oncocytoma (left of image) and a slice of a normal kidney (right of image). Note the rounded contour, the mahogany colour and the central scar. In gross appearance, the tumors are tan or mahogany brown, well circumscribed and contain a central scar. They may achieve a large size (up to 12 cm in diameter).
This is an accepted version of this page This is the latest accepted revision, reviewed on 21 February 2025. Medical condition Kidney cancer Other names Renal cancer Micrograph showing the most common type of kidney cancer (clear cell renal cell carcinoma). H&E stain. Specialty Oncology nephrology Urology Symptoms Blood in the urine, lump in the abdomen, back pain Usual onset After the age of ...
Time-to-event studies must have sufficiently long follow-up durations to capture enough events to reveal meaningful patterns in the data. A short follow-up duration is appropriate for studying very severe cancers with poor prognoses , whereas a long follow-up duration is better suited to studying less-severe disease, or participants with good ...
Internal contamination due to ingestion, inhalation, injection, or absorption is a particular concern because the radioactive material may stay in the body for an extended period of time, "committing" the subject to accumulating dose long after the initial exposure has ceased, albeit at low dose rates.
Cytopathology suspicious for Hürthle cell neoplasm (Bethesda category IV, rather than Hürthle cell hyperplasia), Pap stain. [3]While Hurthle cells can occur in healthy thyroid glands, [1] they are often associated with Hashimoto's thyroiditis [4] and Graves' disease.
The dose–response relationship, or exposure–response relationship, describes the magnitude of the response of an organism, as a function of exposure (or doses) to a stimulus or stressor (usually a chemical) after a certain exposure time. [1] Dose–response relationships can be described by dose–response curves. This is explained further ...
A cancer registry is a systematic collection of data about cancer and tumor diseases. The data are collected by Cancer Registrars.Cancer Registrars capture a complete summary of patient history, diagnosis, treatment, and status for every cancer patient in the United States, and other countries.