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The division between prokaryotes and eukaryotes has been considered the most important distinction or difference among organisms. The distinction is that eukaryotic cells have a "true" nucleus containing their DNA, whereas prokaryotic cells do not have a nucleus. [52]
Prokaryotic DNA Replication is the process by which a prokaryote duplicates its DNA into another copy that is passed on to daughter cells. [1] Although it is often studied in the model organism E. coli, other bacteria show many similarities. [2] Replication is bi-directional and originates at a single origin of replication (OriC). [3]
Due to their structural differences, eukaryotic and prokaryotic cells do not divide in the same way. Also, the pattern of cell division that transforms eukaryotic stem cells into gametes (sperm cells in males or egg cells in females), termed meiosis, is different from that of the division of somatic cells in the body. Cell division over 42.
Unlike bacteria, eukaryotic DNA replicates in the confines of the nucleus. [52] The G1/S checkpoint (restriction checkpoint) regulates whether eukaryotic cells enter the process of DNA replication and subsequent division. Cells that do not proceed through this checkpoint remain in the G0 stage and do not replicate their DNA. [citation needed]
Prokaryotic cells probably transitioned into eukaryotic cells between 2.0 and 1.4 billion years ago. [31] This was an important step in evolution. In contrast to prokaryotes, eukaryotes reproduce by using mitosis and meiosis. Sex appears to be a ubiquitous and ancient, and inherent attribute of eukaryotic life. [32]
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
Some eukaryotic cells (plant cells and fungal cells) also have a cell wall. Inside the cell is the cytoplasmic region that contains the genome (DNA), ribosomes and various sorts of inclusions. [2] The genetic material is freely found in the cytoplasm. Prokaryotes can carry extrachromosomal DNA elements called plasmids, which are
Prokaryotes do have DNA repair mechanism enriched with recombinational repair, [23] and the existence of prokaryotic life in severe environment indicates the extreme efficiency of this mechanism to help them survive many DNA damages related to the environment. This implies that an extra costly repair in the form of meiosis would be unnecessary.