enow.com Web Search

Search results

1. Results from the WOW.Com Content Network

2. Immunoglobulin M - Wikipedia

   en.wikipedia.org/wiki/Immunoglobulin_M

   Immunoglobulin M (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first antibody to appear in the response to initial exposure to an antigen ; [ 1 ] [ 2 ] causing it to also be called an acute phase antibody.

3. ABO blood group system - Wikipedia

   en.wikipedia.org/wiki/ABO_blood_group_system

   The associated anti-A and anti-B antibodies are usually IgM antibodies, produced in the first years of life by sensitization to environmental substances such as food, bacteria, and viruses. The ABO blood types were discovered by Karl Landsteiner in 1901; he received the Nobel Prize in Physiology or Medicine in 1930 for this discovery. [ 5 ]

4. Immunoglobulin class switching - Wikipedia

   en.wikipedia.org/wiki/Immunoglobulin_class_switching

   Mechanism of class-switch recombination that allows isotype switching in activated B cells. Immunoglobulin class switching, also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell's production of immunoglobulin from one type to another, such as from the isotype IgM to the isotype IgG. [1]

5. Isotype (immunology) - Wikipedia

   en.wikipedia.org/wiki/Isotype_(immunology)

   As IgM antibodies are expressed early in a B cell response, they are rarely highly mutated and have broad antigen reactivity thus providing an early response to a wide range of antigens without the need for T cell help. [5] IgD isotypes are expressed on naive B cells as they leave bone marrow and populate secondary lymphoid organs.

6. Antibody - Wikipedia

   en.wikipedia.org/wiki/Antibody

   The antibody isotype of a B cell changes during cell development and activation. Immature B cells, which have never been exposed to an antigen, express only the IgM isotype in a cell surface bound form. The B lymphocyte, in this ready-to-respond form, is known as a "naive B lymphocyte." The naive B lymphocyte expresses both surface IgM and IgD.

7. Organization and expression of immunoglobulin genes

   en.wikipedia.org/wiki/Organization_and...

   The mature B cell formed as RNA processing changes leaves the bone marrow and is stimulated by the antigen then differentiated into IgM -secreted plasma cells. Also at first, the mature B cell expresses membrane-bound IgD and IgM. These two classes could switch to secretory IgD and IgM during the processing of mRNAs.