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Common behavioral treatments for childhood narcolepsy include improved sleep hygiene, scheduled naps, and physical exercise. [68] Many medications are used in treating adults and may be used to treat children. These medications include central nervous system stimulants such as methylphenidate, modafinil, amphetamine, and dextroamphetamine. [69]
Treatment for narcolepsy and cataplexy can be divided to those that act on the excessive daytime sleepiness (EDS) and those that improve cataplexy. Most patients require lifelong use of medications. [15] Most treatments in humans will act only symptomatically and do not target the loss of the orexin-producing neurons. [16]
Pediatric narcolepsy cases are cases when patients are diagnosed or experience symptoms onset for narcolepsy before the age of 18. Of patients who obtain a formal diagnosis for narcolepsy, more than 50% report first experiencing symptoms of narcolepsy more than 10 years before their formal diagnosis, with an average age of symptom onset being at age 15 and symptom onset most likely to occur ...
Pitolisant, sold under the brand name Wakix among others, is a medication used for the treatment of excessive daytime sleepiness in adults with narcolepsy. [3] It is an inverse agonist of the histamine 3 (H 3) receptor (an antihistamine drug specific to that kind of receptors). [3]
Sodium oxybate, sold under the brand name Xyrem among others, is a medication used to treat symptoms of narcolepsy: sudden muscle weakness and excessive daytime sleepiness. [3] [7] [8] It is used sometimes in France and Italy as an anesthetic given intravenously; [9]: 15, 27–28 it is also approved and used in Italy and in Austria to treat alcohol dependence and alcohol withdrawal syndrome.
Finally, he had a diagnosis — type one narcolepsy with cataplexy, the most common form of the disease. ... There is no drug to treat narcolepsy, but medications can tackle some of the worst ...
Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...
Solriamfetol, sold under the brand name Sunosi, is a wakefulness-promoting medication used in the treatment of excessive sleepiness related to narcolepsy and sleep apnea. [1] [5] [6] It is taken by mouth. [1] Common side effects of solriamfetol include headache, nausea, anxiety, and trouble sleeping. [1]
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