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The pharmacokinetics of ethanol are well characterized by the ADME acronym (absorption, distribution, metabolism, excretion). Besides the dose ingested, factors such as the person's total body water, speed of drinking, the drink's nutritional content, and the contents of the stomach all influence the profile of blood alcohol content (BAC) over ...
Longer timeframes for drinking alcohol can lead to higher consumption and blood alcohol levels, Dr. Issac explains. So, you don't just feel drunker after a day of drinking—you are drunker. 2.
NHTSA reports that the following blood alcohol levels (BAC) in a driver will have the following predictable effects on his or her ability to drive safely: (1) A BAC of .02 will result in a "[d]ecline in visual functions (rapid tracking of a moving target), a decline in the ability to perform two tasks at the same time (divided attention)"; (2 ...
Heavy alcohol consumption over a period of years can lead to "reverse tolerance". A liver can be damaged by chronic alcohol use, leading to a buildup of fat and scar tissue. [ 2 ] The reduced ability of such a liver to metabolize or break down alcohol means that small amounts can lead to a high blood alcohol concentration (BAC) and more rapid ...
5. Alcohol Disrupts Your Sleep. Yes, it can feel like a nightcap helps you drift off. But alcohol can disrupt your sleep quite a bit. It can trigger insomnia, obstructive sleep apnea, short sleep ...
Alcohol does not necessarily kill brain cells. [376] Alcohol can, however, lead indirectly to the death of brain cells in two ways. First, in chronic, heavy alcohol users whose brains have adapted to the effects of alcohol, abrupt ceasing following heavy use can cause excitotoxicity leading to cellular death in multiple areas of the brain. [377]
Alcohol use disorder (AUD) is defined as a medical condition characterized by an impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences. [124] Excessive alcohol use can lead to health-related illness and continuous alcohol engagement can ultimately lead to death.
The level of ethanol consumption that minimizes the risk of disease, injury, and death is subject to some controversy. [16] Several studies have found a J-shaped relationship between alcohol consumption and health, [17] [18] [2] [19] meaning that risk is minimized at a certain (non-zero) consumption level, and drinking below or above this level increases risk, with the risk level of drinking a ...
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