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Endothelial PAS domain-containing protein 1 (EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2α)) is a protein that is encoded by the EPAS1 gene in mammals. It is a type of hypoxia-inducible factor , a group of transcription factors involved in the physiological response to oxygen concentration.
This compaction makes the gene promoter inaccessible without the assistance of other factors in the nucleus, and thus chromatin structure is a common site of regulation. Similar to the sigma factors in prokaryotes, the general transcription factors (GTFs) are a set of factors in eukaryotes that are required for all transcription events.
The transcription preinitiation complex is a large complex of proteins that is necessary for the transcription of protein-coding genes in eukaryotes and archaea. It attaches to the promoter of the DNA (e.i., TATA box) and helps position the RNA polymerase II to the gene transcription start sites, denatures the DNA, and then starts transcription.
[1] [2] FOX proteins also have pioneering transcription activity by being able to bind condensed chromatin during cell differentiation processes. [ 3 ] The defining feature of FOX proteins is the forkhead box , a sequence of 80 to 100 amino acids forming a motif that binds to DNA .
6908 21374 Ensembl ENSG00000112592 ENSMUSG00000014767 UniProt P20226 P29037 RefSeq (mRNA) NM_003194 NM_001172085 NM_013684 RefSeq (protein) NP_001165556 NP_003185 NP_038712 Location (UCSC) Chr 6: 170.55 – 170.57 Mb Chr 17: 15.72 – 15.75 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Protein family TBP crystal structure of a yeast brf1-tbp-dna ternary complex Identifiers Symbol ...
Transcriptionists listen to videos and audio files and convert spoken words into written text. This work is necessary in a wide range of industries, including healthcare, legal, and marketing, to ...
EGR-1 (Early growth response protein 1) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. EGR-1 is a mammalian transcription factor . It was also named Krox-24, TIS8, and ZENK .
Transcription specialist. Data entry. 1. Medical Transcriptionist. Average annual salary: $30,100 to $43,503. Working from home lends itself well to medical transcription. It does help if you are ...
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