Search results
Results from the WOW.Com Content Network
A Howell–Jolly body (marked by arrow) within an erythrocyte. A Howell–Jolly body is a cytopathological finding of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes. During maturation in the bone marrow, late erythroblasts normally expel their nuclei; but, in some cases, a small portion of DNA remains. The presence of ...
Normal red blood cells are round, flattened disks that are thinner in the middle than at the edges. A poikilocyte is an abnormally-shaped red blood cell. [1] Generally, poikilocytosis can refer to an increase in abnormal red blood cells of any shape, where they make up 10% or more of the total population of red blood cells.
Howell-Jolly body-like inclusions (HJBLi) are a hematopathological finding of an inclusion arising from detached DNA nuclear fragment in white blood cells caused by dysplastic granulopoiesis. [1] The inclusion is aptly named for its similar appearance of the Howell–Jolly body in erythrocytes. [2] The term was coined in 1989. [2]
Theodor Boveri originally observed the fact that abnormal nuclear morphologies commonly occur in cancer.Micronuclei are also referred to Howell-Jolly bodies; discovered by hematologists William Henry Howell and Justin Marie Jolly in erythrocytes.
Codocytes in human blood (Giemsa stain) Target cell compared to other forms of poikilocytosis.Codocytes, also known as target cells, are red blood cells that have the appearance of a shooting target with a bullseye.
Blood smear showing red blood cells with basophilic stippling. Basophilic stippling, also known as punctate basophilia, is the presence of numerous basophilic granules that are dispersed through the cytoplasm of erythrocytes in a peripheral blood smear.
They are believed to be microtubules that are remnants from a mitotic spindle, and their presence indicates an abnormality in the production of red blood cells. [1] Cabot Rings, considerably rare findings, when present are found in the cytoplasm of red blood cells and in most cases, are caused by defects of erythrocytic production [ 2 ] and are ...
The number of micronuclei per cell can be predicted using the following formula: / = / AF is the number of acentric fragments and F = 0.5 - 0.5P, where P equals the probability of fragments being included in the traditional nucleus and not forming a micronucleus.