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Diastolic blood pressure falls during the early stages of sepsis, causing a widening/increasing of pulse pressure, which is the difference between the systolic and diastolic blood pressures. If sepsis becomes severe and hemodynamic compromise advances, the systolic pressure also decreases, causing a narrowing/decreasing of pulse pressure. [23]
Septic shock refers specifically to distributive shock due to sepsis as a result of infection. [14] Septic shock may be defined as sepsis-induced low blood pressure that persists despite treatment with intravenous fluids. [9] Low blood pressure reduces tissue perfusion pressure, causing the tissue hypoxia that is characteristic of shock.
A pulse pressure is considered abnormally low if it is less than 25% of the systolic value. [2] If the pulse pressure is extremely low, i.e. 25 mmHg or less, it may indicate low stroke volume, as in congestive heart failure. [3] The most common cause of a low (narrow) pulse pressure is a drop in left ventricular stroke volume.
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There are four types of distributive shock. The most common, septic shock, is caused by an infection, most frequently by bacteria, but viruses, fungi and parasites have been implicated. [3] Infection sites most likely to lead to septic shock are chest, abdomen and genitourinary tract. [3]
Bacteremia is clinically distinct from sepsis, which is a condition where the blood stream infection is associated with an inflammatory response from the body, often causing abnormalities in body temperature, heart rate, breathing rate, blood pressure, and white blood cell count. [42]
She went into sepsis, a life-threatening condition that occurs when the body’s infection-fighting processes turn on itself, causing the organs to work poorly. Her lungs, kidneys, liver and other ...
Hyperdynamic circulation is abnormally increased circulatory volume. Systemic vasodilation and the associated decrease in peripheral vascular resistance results in decreased pulmonary capillary wedge pressure and decreased blood pressure, presenting usually with a collapsing pulse, but sometimes a bounding pulse.