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During oogenesis, the oogonia become primary oocytes. Oocytes (immature ova) residing in the primordial follicle of the ovary are in a non-growing prophase arrested state, but have the capacity to undergo highly efficient homologous recombinational repair of DNA damages including double-strand breaks. [1]
Oogenesis (/ ˌ oʊ. ə ˈ dʒ ɛ n ɪ s ɪ s /) or ovogenesis is the differentiation of the ovum (egg cell) into a cell competent to further develop when fertilized. [1] It is developed from the primary oocyte by maturation.
This is an accepted version of this page This is the latest accepted revision, reviewed on 10 February 2025. Procreative biological processes of humanity Part of a series on Sex Biological terms Sexual dimorphism Sexual differentiation Feminization Virilization Sex-determination system XY XO ZW ZO Temperature-dependent Haplodiploidy Heterogametic sex Homogametic sex Sex chromosome X chromosome ...
The zona pellucida is a translucent matrix of cross-linked glycoprotein filaments that surrounds the mammalian oocyte and is 6.5–20 μm thick depending on the species. Its formation, which depends on a conserved zona pellucida-like (ZP) module that mediates the polymerization of egg coat components, [2] is critical to successful fertilization. [3]
It is theorized that oogonia either degenerate or differentiate into primary oocytes which enter oogenesis and are halted in prophase I of the first meiosis post partum. Therefore, it is believed that adult mammalian females lack a population of germ cells that can renew or regenerate, and instead have a large population of primary oocytes that ...
Lampbrush chromosomes produce a large number of mRNAs and non-coding RNAs, which are synthesized on the lateral loops. These transcripts are used during oogenesis and at the early stages of embryogenesis. Each lateral loop contains one or several transcription units with polarized RNP-matrix coating the DNA axis of the loop. [5] [6] [7]
Gametogenesis, the development of diploid germ cells into either haploid eggs or sperm (respectively oogenesis and spermatogenesis) is different for each species but the general stages are similar. Oogenesis and spermatogenesis have many features in common, they both involve: Meiosis; Extensive morphological differentiation
The border cells are a cluster of 6–8 cells that migrate in the ovariole of the fruit-fly Drosophila melanogaster, during the process of oogenesis.A fly ovary consists of a string of ovarioles or egg chambers arranged in an increasing order of maturity.