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There is an association between rheumatoid factor and more persistently active synovitis, more joint damage, greater eventual disability and arthritis. [12] [13] Other than in rheumatoid arthritis, rheumatoid factor may also be elevated in other conditions, including: Systemic lupus erythematosus (SLE) [14] [15] Sjögren syndrome [14] [15]
The typical rheumatoid nodule may be a few millimetres to a few centimetres in diameter and is usually found over bony prominences, such as the elbow, the heel, the knuckles, or other areas that sustain repeated mechanical stress. Nodules are associated with a positive RF (rheumatoid factor) titer, ACPA, and severe erosive arthritis. Rarely ...
Polyarthritis is often caused by an auto-immune disorder such as rheumatoid arthritis, psoriatic arthritis, and lupus erythematosus, or other inflammatory rheumatic diseases, like crystal arthropathies. It can also be caused by cancer or various medications. [1] Another cause of polyarthritis is infection, which may be viral or bacterial. [1]
Poor prognostic factors include arthritis of the hip, cervical spine, ankles or wrists; prolonged elevation of inflammatory markers; and radiographic evidence of joint damage including erosions or joint space narrowing. Patients with RF-positive polyarthritis often have worse outcomes associated with more aggressive disease.
This was later revised in 2001. In this classification juvenile idiopathic arthritis is the umbrella term and comprises seven categories: systemic arthritis, oligoarthritis, polyarthritis (reumatic factor negative), polyarthritis (reumatic factor positive), psoriatic arthritis, enthesitis related arthritis and undifferntiatied arthritis. [4]
Rheumatoid factor may be present especially in the group that is likely to develop rheumatoid arthritis. Proposed classification by Guerne and Weismann in 1992: [8] A 6-month history of brief sudden-onset and recurrent episodes of monoarthritis or rarely polyarthritis or of soft tissue inflammation. Direct observation of one attack by a physician.
Positive rheumatoid factor polyarthritis; Post-polio syndrome; Post Traumatic Stress disorder (PTSD) Postaxial polydactyly mental retardation; Posterior tibial tendon rupture; Posterior urethral valves; Posterior uveitis; Posterior valve urethra; Post-infectious myocarditis; Post-partum depression; Post-traumatic epilepsy; Postural hypotension
Remitting seronegative symmetrical synovitis with pitting edema (or sometimes RS 3 PE) is a rare syndrome identified by symmetric polyarthritis, synovitis, acute pitting edema (swelling) of the back of the hands and/or feet, and a negative serum rheumatoid factor. [2]