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Vibegron, sold under the brand name Gemtesa, is a medication for the treatment of overactive bladder. [ 1 ] [ 5 ] [ 6 ] Vibegron is a selective beta-3 adrenergic receptor agonist . [ 1 ]
Sitagliptin was approved by the US Food and Drug Administration (FDA) in October 2006, [30] and is sold under the brand name Januvia. [31] In April 2007, the FDA approved an oral combination of sitagliptin/metformin sold under the brand name Janumet. [ 32 ]
Common adverse drug reactions (≥1% of patients) associated with ezetimibe therapy include headache and/or diarrhea (steatorrhea). Infrequent adverse effects (0.1–1% of patients) include myalgia and/or raised liver function test (ALT/AST) results. Rarely (<0.1% of patients), hypersensitivity reactions (rash, angioedema) or myopathy may occur ...
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Automatic Generic Substitution is a proposal by the Department of Health (DH) whereby in January 2010 pharmacists could be obliged to substitute a generic version (a version of the drug with the same active ingredient) of a medication even if the prescriber had written the prescription for a specific brand, as part of a new deal on drug pricing.
It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US). Ezetimibe reduces blood cholesterol by acting at the brush border of the small intestine and inhibiting the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver.
Donnatal® is considered part of the DESI drug category and currently is listed as one of 14 drugs still under evaluation by the FDA. [15] In response to FDA questions about Donnatal® efficacy, A. H. Robins Co. filed abbreviated new drug applications for Donnatal® tablets (ANDA 86-676), capsules (ANDA 86-677), and Elixir (ANDA 86-661). [ 16 ]
Dextropropoxyphene [5] is an analgesic in the opioid category, patented in 1955 [6] and manufactured by Eli Lilly and Company.It is an optical isomer of levopropoxyphene.It is intended to treat mild pain and also has antitussive (cough suppressant) and local anaesthetic effects.