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Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor (lesser periwinkle), comprising about 25–65% of its indole alkaloids by weight. It can also be synthesized from related alkaloids. [1]
Vinca difformis in habitat, Cáceres, Spain. Vinca plants are subshrubs or herbaceous, and have slender trailing stems 1–2 m (3 + 1 ⁄ 2 – 6 + 1 ⁄ 2 ft) long but not growing more than 20–70 cm (8– 27 + 1 ⁄ 2 in) above ground; the stems frequently take root where they touch the ground, enabling the plant to spread widely.
Vinca major is a trailing vine, spreading along the ground and rooting along the stems to form dense masses of groundcover individually 2–5 metres (6 + 1 ⁄ 2 – 16 + 1 ⁄ 2 ft) across and up to 25 centimetres (10 in) high, perhaps even 50–70 cm (20–28 in).
Vinca minor (common names lesser periwinkle [1] or dwarf periwinkle) is a species of flowering plant in the dogbane family, native to central and southern Europe. Other vernacular names used in cultivation include small periwinkle , common periwinkle , and sometimes in the United States, myrtle or creeping myrtle .
Additional researched vinca alkaloids include vincaminol, vineridine, and vinburnine. Vinpocetine is a semi-synthetic derivative of vincamine (sometimes described as "a synthetic ethyl ester of apovincamine"). [14] Minor vinca alkaloids include minovincine, methoxyminovincine, minovincinine, vincadifformine, desoxyvincaminol, and vincamajine ...
Vinpocetine (ethyl apovincaminate) is a synthetic derivative of the vinca alkaloid vincamine, differing by the removal of a hydroxyl group and by being the ethyl rather than the methyl ester of the underlying carboxylic acid. Vincamine is extracted from either the seeds of Voacanga africana or the leaves of Vinca minor (lesser periwinkle).
Akuammine (vincamajoridine [2]) is an indole alkaloid.It is the most abundant alkaloid found in the seeds from the tree Picralima nitida, [3] commonly known as akuamma, comprising 0.56% of the dried powder.
Vincaminol (C 20 H 26 N 2 O 2) is a chemical that is a part of the Vinca alkaloid group, which were discovered in the 1950s and are derived from Vinca minor (periwinkle). [1] [2] Vincaminol is not as well known as some of the other Vinca alkaloids such as vinblastine, vinorelbine, vincristine, and vindesine, which are the most medically useful Vinca alkaloids.
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