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Between 2014 and 2017, the FDA stated they did not have enough data to determine whether the REMS program was sufficiently preventing opioid abuse. [9] The Health and Human Services Office of the Inspector General recommended that parties in the REMS program provide the FDA more data. [ 10 ]
Substance abuse prevention, also known as drug abuse prevention, is a process that attempts to prevent the onset of substance use or limit the development of problems associated with using psychoactive substances. Prevention efforts may focus on the individual or their surroundings.
Opioids work by affecting the brain cells and reducing the perception of pain. [7] Other side effects include euphoria, mood changes, and the clouding or complete loss of consciousness. [8] Due to their high potential misuse and addictive properties, opioids are highly regulated and controlled by healthcare departments. [9] [10]
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The state and L.A. County have worked hard to make Naloxone more widely available. One of the hurdles, though, has been the price of the inhalable version, Narcan.
The Centers for Disease Control and Prevention (CDC) determined synthetic opioids, like fentanyl, to be the main culprit in increased U.S. opioid-related deaths. [6] In 2017, 38.9% of drug overdose deaths in the U.S. involved fentanyl. [ 7 ]
The opioid epidemic took hold in the U.S. in the 1990s. Percocet, OxyContin and Opana became commonplace wherever chronic pain met a chronic lack of access to quality health care, especially in Appalachia. The Centers for Disease Control and Prevention calls the prescription opioid epidemic the worst of its kind in U.S. history.
Naloxone was created in a laboratory, patented in 1961, and approved by the FDA a decade later. [1] It was first proposed in the 1990s for community-based provisions of take-home naloxone rescue kits (THN) to opioid users, which involved training opioid users, along with their family or friends, in awareness, emergency management, and administration of naloxone. [2]