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  2. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    [20] [21] [22] In the United States, the Food and Drug Administration (FDA) has advised that over-the-counter PPIs, such as Prilosec OTC, should be used no more than three 14-day treatment courses over one year. [23] [24] Despite their extensive use, the quality of the evidence supporting their use in some of these conditions is variable.

  3. Omeprazole - Wikipedia

    en.wikipedia.org/wiki/Omeprazole

    Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. [1] It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. [1]

  4. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    A new approach for the treatment of acid-related diseases was introduced, and omeprazole was quickly shown to be clinically superior to the histamine H 2 receptor antagonists, and was launched in 1988 as Losec in Europe, and in 1990 as Prilosec in the United States. In 1996, Losec became the world's biggest ever selling pharmaceutical, and by ...

  5. Chronic kidney disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_kidney_disease

    The term "non-dialysis-dependent chronic kidney disease" (NDD-CKD) is a designation used to encompass the status of those persons with an established CKD who do not yet require the life-supporting treatments for kidney failure known as kidney replacement therapy (RRT, including maintenance dialysis or kidney transplantation).

  6. Kidney disease - Wikipedia

    en.wikipedia.org/wiki/Kidney_disease

    Chronic kidney disease is defined as prolonged kidney abnormalities (functional and/or structural in nature) that last for more than three months. [1] Acute kidney disease is now termed acute kidney injury and is marked by the sudden reduction in kidney function over seven days.

  7. AstraZeneca to pay $425 million to end US lawsuits over ... - AOL

    www.aol.com/astrazeneca-pay-425-million-end...

    AstraZeneca did not disclose specific terms of the agreement and said in a statement on Tuesday that it continues to believe the claims are without merit and admitted no wrongdoing. It is the ...

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