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Phage therapy, viral phage therapy, or phagotherapy is the therapeutic use of bacteriophages for the treatment of pathogenic bacterial infections. [ 1 ] [ 2 ] [ 3 ] This therapeutic approach emerged at the beginning of the 20th century but was progressively replaced by the use of antibiotics in most parts of the world after the Second World War .
Several laboratories have been testing suitability of bacteriophage isolates to control certain bacterial pathogens. Significant advancements in this research have been made at the Bacteriophage Institute in Tbilisi, Georgia, where phage therapy is routinely applied in medicine research. Today treatment of antibiotic resistant bacteria is a ...
In July 2007, the same bacteriophage were approved for use on all food products. [37] In 2011 USDA confirmed that LISTEX is a clean label processing aid and is included in USDA. [38] Research in the field of food safety is continuing to see if lytic phages are a viable option to control other food-borne pathogens in various food products. [39]
Phage therapy is the method by which bacteriophages (viruses which infect bacteria) are used to treat bacterial infections or reduce bacterial populations. Phage therapy has gained recent attention in the United States as an alternative to standard antibiotic therapy.
A more detailed account of the use of phage in major biological discoveries can be found on the page, bacteriophage. As one of the earliest applied microbiologists, d'Hérelle's microbe-centered worldview has been noted for its prescience, since microbes are playing increasingly important roles in bioremediation , microbial fuel cells , gene ...
Research Styles in Virus Studies in the Twentieth Century: Controversies and the Formation of Consensus. Doctoral Thesis, University of Limburg. (note that though this is a thesis, it is of sufficient general interest toward addressing issues in the history of bacteriophagy as to warrant inclusion in this list)
Mycobacteriophage Bxb1 Structure [1]. A mycobacteriophage is a member of a group of bacteriophages known to have mycobacteria as host bacterial species. While originally isolated from the bacterial species Mycobacterium smegmatis and Mycobacterium tuberculosis, [2] the causative agent of tuberculosis, more than 4,200 mycobacteriophage species have since been isolated from various environmental ...
A bacteriophage, or phage for short, is a virus that can infect bacteria and archaea, and can replicate inside of them. Phages make up the majority of most viromes and are currently understood as being the most abundant organism. [5] Oftentimes scientists will look only at a phageome instead of a virome while conducting research.