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attenuation. [ah-ten″u-a´shun] 1. the act of thinning or weakening. 2. the change in the virulence of a pathogenic microorganism induced by passage through another host species, decreasing its virulence for the native host and increasing it for the new host.
Weakened or reduced, and so altered in characteristics so as no longer to be dangerous. The term is applied to organisms that have been specially cultured so as to reduce their virulence and make them suitable for use in vaccines. Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005.
attenuate. (ə-tĕn′yo͞o-āt′) v. attenu·ated, attenu·ating, attenu·ates. v.tr. 1. To reduce in force, value, amount, or degree; weaken: Medicine attenuated the fever's effect. 2. To lessen the density of; rarefy. 3.
1. the act of thinning or weakening. 2. the change in the virulence of a pathogenic microorganism induced by passage through another host species, decreasing its virulence for the native host and increasing it for the new host. This is the basis for the development of live vaccines.
attenuate. (ə-tĕn′yo͞o-āt′) v. attenu·ated, attenu·ating, attenu·ates. v.tr. 1. To reduce in force, value, amount, or degree; weaken: Medicine attenuated the fever's effect. 2. To lessen the density of; rarefy. 3.
1. the act of thinning or weakening. 2. the change in the virulence of a pathogenic microorganism induced by passage through another host species, decreasing its virulence for the native host and increasing it for the new host. This is the basis for the development of live vaccines.
1. the act of thinning or weakening. 2. the change in the virulence of a pathogenic microorganism induced by passage through another host species, decreasing its virulence for the native host and increasing it for the new host. This is the basis for the development of live vaccines.
attenuation value. A measure of an imaging beam’s reduction in intensity by the tissue through which it passes. Examples, attenuation values Air has a negative AV; fluids have an AV up to the low 30s; non-calcified solid masses to the low 70s; calcified masses up to 100. Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
attenuated vaccine a vaccine prepared from live microorganisms or viruses cultured under adverse conditions, leading to loss of their virulence but retention of their ability to induce protective immunity.
interaural attenuation. the reduction in intensity, at one ear, of an acoustic stimulus presented to the other ear canal as the sound is transmitted through the head; for air conduction, the reduction approximates 35 dB, but for bone conduction, it is 10 dB or less. Farlex Partner Medical Dictionary © Farlex 2012.