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  2. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Formulations are 500/1, 500/2, 500/4, 1000/2, and 1000 mg/4 mg of metformin/rosiglitazone. In 2009, it was the most popular metformin combination. [178] In 2005, the stock of Avandamet was removed from the market, after inspections showed the factory where it was produced was violating good manufacturing practices. [179]

  3. Empagliflozin/metformin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin/metformin

    Empagliflozin/metformin was approved for use in the European Union in May 2015. [5] Empagliflozin/metformin was approved for use in the United States in August 2015. [6] [11] The extended release version was approved for use in the United States in December 2016. [12] [13] Empagliflozin/metformin was approved for use in Australia in May 2020. [2]

  4. Sitagliptin/metformin - Wikipedia

    en.wikipedia.org/wiki/Sitagliptin/metformin

    It contains sitagliptin (a dipeptidyl peptidase-4 inhibitor) and metformin (a biguanide). [5] The combination was approved for medical use in the United States in 2007. [5] In 2022, it was the 182nd most commonly prescribed medication in the United States, with more than 2 million prescriptions. [12] [13] It is available as a generic medication ...

  5. Empagliflozin/linagliptin/metformin - Wikipedia

    en.wikipedia.org/.../linagliptin/metformin

    To reduce the risk of developing ketoacidosis (a serious condition where the body produces high levels of blood acids called ketones) after surgery, the FDA has approved changes to the prescribing information for SGLT2 inhibitor diabetes medications, recommending they be temporarily stopped before scheduled surgery.

  6. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Using gliflozins in combination therapy with metformin can lower the risk of hypoglycemia compared to other type 2 diabetes treatments such as sulfonylureas and insulin. [ 12 ] Increased risk of lower limb amputation is associated with canagliflozin but further data is needed to confirm this risk associated with different gliflozins. [ 16 ]

  7. Diabetes medication - Wikipedia

    en.wikipedia.org/wiki/Diabetes_medication

    Phenformin (DBI) was used from 1960s through 1980s, but was withdrawn due to lactic acidosis risk. [11] Buformin also was withdrawn due to lactic acidosis risk. [12] Metformin is a first-line medication used for treatment of type 2 diabetes.

  8. Vildagliptin/metformin - Wikipedia

    en.wikipedia.org/wiki/Vildagliptin/metformin

    It was approved for use in the European Union in November 2007, [4] and the approval was updated in 2008. [ 5 ] [ 6 ] [ 7 ] It combines 50 mg vildagliptin with either 500, 850, or 1000 mg metformin .

  9. Dapagliflozin - Wikipedia

    en.wikipedia.org/wiki/Dapagliflozin

    In combination with metformin, dapagliflozin at standard treatment dose of 10 mg daily lowered HbA1c by 0.54-0.84% (5.9-9.3 mmol/mol) when compared to metformin monotherapy in patients with inadequately controlled type 2 diabetes and normal renal function. [48] [49] [50]

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