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Ambroxol is a drug that breaks up phlegm, used in the treatment of respiratory diseases associated with viscid or excessive mucus. Ambroxol is often administered as ...
The proportion of domperidone excreted unchanged is small (10% in feces and 1% in urine). [9] The elimination half-life of domperidone is about 7 to 9 hours in healthy individuals. [ 9 ] [ 2 ] However, the elimination half-life of domperidone can be prolonged to 20 hours in people with several renal dysfunction .
[1] [2] [3] It acts as a selective dopamine D 2 and D 3 receptor antagonist and has peripheral selectivity. [ 2 ] [ 3 ] Deudomperidone is a deuterated form of domperidone , and it is suggested that deudomperidone may have improved efficacy , tolerability , and pharmacokinetics compared to domperidone.
These include for adults: antihistamines, antihistamine-decongestant combinations, benzonatate, anti asthmatic-expectorant-mucolytic combinations, expectorant-bronchodilator combinations, leukotriene inhibitors, ambroxol, and guaifenesin, sometimes with analgesics, antipyretics, anti inflammatories, and anticholinergics; and for children ...
Erdosteine is a molecule with mucolytic activity. Structurally it is a thioether derivative with two thioether groups. [1] These two functional organosulfur groups contained in the molecule are released following first-pass metabolism with the conversion of erdosteine into its pharmacologically active metabolite Met-I.
Dopamine receptor flow chart. Dopamine receptors are all G protein–coupled receptors, and are divided into two classes based on which G-protein they are coupled to. [1] The D 1-like class of dopamine receptors is coupled to Gα s/olf and stimulates adenylate cyclase production, whereas the D 2-like class is coupled to Gα i/o and thus inhibits adenylate cyclase production.
Levosulpiride, sold under the brand names Dislep and Sulpepta among others, is a dopamine antagonist medication which is used in the treatment of psychotic disorders like schizophrenia, major depressive disorder, nausea and vomiting, and gastroparesis.
Methyldopa acts on alpha-2 adrenergic receptors, which are found on the pre synaptic nerve terminal. [1] This inhibits the release of norepinephrine from the presynaptic neuron. The S-enantiomer of methyldopa is a competitive inhibitor of the enzyme aromatic L -amino acid decarboxylase (LAAD), which converts L -DOPA into dopamine .