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SSRIs have dominated the market for antidepressants [1] and are recommended by the National Institute for Health and Clinical Excellence (NICE) as a first-line treatment of depression, because they tend to have fewer adverse effects than other type of antidepressants with the same effectiveness. [4]
The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
In Canada, SSRIs are a first-line treatment of adult obsessive–compulsive disorder (OCD). In the UK, they are first-line treatment only with moderate to severe functional impairment and as second line treatment for those with mild impairment, though, as of early 2019, this recommendation is being reviewed. [ 26 ]
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
Depression rates among people 60 and older hover at just under 6%, which is lower than the population as a whole. However, it’s important to know that for adults 85 and older, the rate of ...
For people with a history of moderate or severe depression. For people with mild depression that has been present for an extended period. As a first-line treatment for moderate to severe depression. As a second-line treatment for mild depression that persists after other interventions.
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