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In general, TERRA has been shown to be most abundant in cells with long telomeres, [2] [3] while cells with short telomeres express comparatively lower levels of transcript expression. There is also evidence that overexpression of TERRA in human cells can help promote telomere processing by inhibiting the 5'-3' exonuclease Exo1 through the Ku70 ...
n/a Ensembl ENSG00000277925 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 3: 169.76 – 169.77 Mb n/a PubMed search n/a Wikidata View/Edit Human RNA family Vertebrate telomerase RNA Identifiers Symbol Telomerase-vert Rfam RF00024 Other data RNA type Gene Domain(s) Eukaryote ; Virus PDB structures PDBe RNA family Ciliate telomerase RNA Identifiers Symbol ...
TERRA in biology is an abbreviation for "TElomeric Repeat-containing RNA". [1] TERRA is RNA that is transcribed from telomeres — the repeating 6-nucleotide sequences that cap the ends of chromosomes. TERRA functions with shelterin to inhibit telomere lengthening by enzyme telomerase. [1]
This is an accepted version of this page This is the latest accepted revision, reviewed on 30 January 2025. Classified advertisements website Craigslist Inc. Logo used since 1995 Screenshot of the main page on January 26, 2008 Type of business Private Type of site Classifieds, forums Available in English, French, German, Dutch, Spanish, Italian, Portuguese Founded 1995 ; 30 years ago (1995 ...
It is known to protect telomeres in mammals from DNA mechanisms that are used for repair purposes and at the same time regulate the activity carried out by telomerase. The telomeric repeat binding factor 1 protein is present at telomeres, where the cells aging aspect is monitored, throughout the typical cell cycle process. [ 7 ]
A telomere (/ ˈ t ɛ l ə m ɪər, ˈ t iː l ə-/; from Ancient Greek τέλος (télos) 'end' and μέρος (méros) 'part') is a region of repetitive nucleotide sequences associated with specialized proteins at the ends of linear chromosomes (see Sequences). Telomeres are a widespread genetic feature most commonly found in eukaryotes.
Telomeres are regions of repetitive DNA at the end of a chromosome, which provide protection from chromosomal deterioration during DNA replication. Recent studies have shown that telomeres function to aid in its own stability. Telomeric repeat-containing RNA (TERRA) are transcripts derived from telomeres. TERRA has been shown to maintain ...
Telomerase, also called terminal transferase, [1] is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of the chromosomes of most eukaryotes .
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