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Guidelines on the choice of agents and how best to step up treatment for various subgroups in hypertension (high blood pressure) have changed over time and differ between countries. A Comparison of International Guidelines on Goal Blood Pressure and Initial Therapy for Adults With Hypertension (adapted from JNC 8 guidelines [ 1 ] )
Guidelines for treating resistant hypertension have been published in the UK [45] and US. [46] It has been proposed that a proportion of resistant hypertension may be the result of chronic high activity of the autonomic nervous system, known as "neurogenic hypertension". [47] Low adherence to treatment is an important cause of resistant ...
BMJ Best Practice is an online decision-support tool made for clinical decision making support. It was created in 2009 by BMJ. [1] Development
Evidence-Based Nursing is a peer-reviewed healthcare journal covering the field of evidence-based nursing. It is published quarterly by the BMJ Publishing Group and RCN Publishing. It is abstracted and indexed by Index Medicus , Scopus and Excerpta Medica/EMBASE. The journal performs systematically searches of nursing and medical journals.
Although severe hypertension is more common in the elderly, it may occur in children (though very rarely), likely due to metabolic or hormonal dysfunction. In 2014, a systematic review identified women as having slightly higher increased risks of developing hypertensive crises than do men.
Hypertension occurs in around 0.2 to 3% of newborns; however, blood pressure is not measured routinely in healthy newborns. [42] Hypertension is more common in high risk newborns. A variety of factors, such as gestational age, postconceptional age and birth weight needs to be taken into account when deciding if a blood pressure is normal in a ...
Home 24h ambulatory Office Home 24h ambulatory American College of Cardiology/American Heart Association (2017) [11] Normal <120 <120 <115 and <80 <80 <75 Elevated 120–129 120–129 115–124 and <80 <80 <75 Hypertension, stage 1 130–139 130–134 125–129 or 80–89 80–84 75–79 Hypertension, stage 2 ≥140 ≥135 ≥130 or ≥90 ≥85 ...
Sildenafil is used as a preventive treatment for altitude-induced pulmonary edema and pulmonary hypertension. [ 38 ] [ 39 ] Sildenafil's mechanism of action is via phosphodiesterase inhibition which raises cGMP, resulting in pulmonary arterial vasodilation and inhibition of smooth muscle cell proliferation and indirectly fluid formation in the ...