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Testosterone cypionate is a testosterone ester and a long-lasting prodrug of testosterone in the body. [7] [2] [3] Because of this, it is considered to be a natural and bioidentical form of testosterone. [14] Testosterone cypionate was introduced for medical use in 1951.
Testosterone esters like testosterone enanthate and testosterone cypionate can be given by subcutaneous injection instead of intramuscular injection. Studies have shown that subcutaneous injection of testosterone and closely related esters in oil like testosterone cypionate , testosterone enantate , and nandrolone decanoate is effective and has ...
Testosterone cypionate and testosterone enanthate were formerly available in combination with estradiol cypionate and estradiol valerate, respectively, under the brand names Depo-Testadiol and Ditate-DS, respectively, as oil solutions for intramuscular injection, but these formulations have been discontinued. [57]
Testosterone can be administered parenterally, but it has more irregular prolonged absorption time and greater activity in muscle in enanthate, undecanoate, or cypionate ester form. These derivatives are hydrolyzed to release free testosterone at the site of injection; absorption rate (and thus injection schedule) varies among different esters ...
Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy in which androgens, often testosterone, are supplemented or replaced. It typically involves the administration of testosterone through injections, skin creams, patches, gels, pills, or subcutaneous pellets.
[4] [5] [22] Along with testosterone enanthate, testosterone cypionate, and testosterone propionate, testosterone undecanoate is one of the most widely used testosterone esters. [16] [7] [11] However, it has advantages over other testosterone esters in that it can be taken by mouth and in that it has a far longer duration when given by injection.
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