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  2. Autoimmunity - Wikipedia

    en.wikipedia.org/wiki/Autoimmunity

    In immunology, autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues and other normal body constituents. [1] [2] Any disease resulting from this type of immune response is termed an "autoimmune disease".

  3. CD20 - Wikipedia

    en.wikipedia.org/wiki/CD20

    Obese mice administered anti-B cell CD-20 antibodies, however, did not become less responsive to insulin and as a result, did not develop diabetes mellitus or the metabolic syndrome, the posited mechanism being that anti-CD20 antibodies rendered the T cell antibodies dysfunctional and therefore powerless to cause insulin insensitivity by a B ...

  4. Type 1 diabetes - Wikipedia

    en.wikipedia.org/wiki/Type_1_diabetes

    Type 1 diabetes is an autoimmune disease where the body attacks the beta-cells produced by the pancreas; therefore, causing the body to have insulin deficiency. [133] Type 1 diabetes is mainly diagnosed in children, and the number of diagnoses is increasing all around the world.

  5. Autoantibody - Wikipedia

    en.wikipedia.org/wiki/Autoantibody

    Antibodies are produced by B cells in two ways: (i) randomly, and (ii) in response to a foreign protein or substance within the body. Initially, one B cell produces one specific kind of antibody. In either case, the B cell is allowed to proliferate or is killed off through a process called clonal deletion. Normally, the immune system is able to ...

  6. Diabetes in Men: What You Need to Know - AOL

    www.aol.com/diabetes-men-know-115800086.html

    When blood sugar levels aren’t managed, untreated diabetes symptoms can lead to several complications throughout the body. According to the American Diabetes Association (ADA), these can include ...

  7. Autoimmune disease - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_disease

    These shared symptoms occur as a result of the body's immune system mistakenly attacking its own cells and tissues, causing inflammation and damage. However, due to the broad range of autoimmune diseases, the specific presentation of symptoms can significantly vary based on the type of disease, the organ systems affected, and individual factors ...

  8. Insulin autoimmune syndrome - Wikipedia

    en.wikipedia.org/wiki/Insulin_autoimmune_syndrome

    The cause of IAS is not clearly understood. However, interaction of disulfide bond in the insulin molecule with sulfhydryl group drugs such as methimazole , carbimazole , captopril , isoniazid , hydralazine , imipenem , and also with lipoic acid has been suggested.

  9. Immune system - Wikipedia

    en.wikipedia.org/wiki/Immune_system

    An antibody is made up of two heavy chains and two light chains. The unique variable region allows an antibody to recognize its matching antigen. [73] A B cell identifies pathogens when antibodies on its surface bind to a specific foreign antigen. [74] This antigen/antibody complex is taken up by the B cell and processed by proteolysis into ...

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