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This spinal interneuron makes an inhibitory synapse onto the alpha motor neuron that innervates the same muscle that caused the Ib afferent to fire. As a result of this reflex, activation of the Ib afferent causes the alpha motor neuron to become inhibited. Thus, the contraction of the muscle stops. [14] This is an example of a disynaptic ...
The spinal cord is a center for coordinating many reflexes and contains reflex arcs that can independently control reflexes. [1] It is also the location of groups of spinal interneurons that make up the neural circuits known as central pattern generators. These circuits are responsible for controlling motor instructions for rhythmic movements ...
It is an essential connection between the body and the brain as well as between the two. The spinal cord has a diameter of 1 to 1.5 cm and a length of 40 to 50 cm. On either side, two successive rows of nerve roots appear. Thirty-one pairs of spinal nerves are formed by the distal union of these nerve roots.
Relay interneurons have long axons and connect circuits of neurons in one region of the brain with those in other regions. [5] However, interneurons are generally considered to operate mainly within local brain areas. [6] The interaction between interneurons allows the brain to perform complex functions such as learning and decision-making.
The central pattern generators are made up of different groups of spinal interneurons. [7] There are four principal types of neural circuits that are responsible for a broad scope of neural functions. These circuits are a diverging circuit, a converging circuit, a reverberating circuit, and a parallel after-discharge circuit. [8]
Neural oscillatory output. Central pattern generators are biological neural networks organized to produce any rhythmic output without requiring a rhythmic input. In mammals, locomotor CPGs are organized in the lumbar and cervical segments of the spinal cord, and are used to control rhythmic muscle output in the arms and legs.
The upper motor neuron descends in the spinal cord to the level of the appropriate spinal nerve root. At this point, the upper motor neuron synapses with the lower motor neuron or interneurons within the ventral horn of the spinal cord, each of whose axons innervate a fiber of skeletal muscle. [1] [2]
Each of these interneuron class can be further divided into diverse subpopulations of neurons with distinct neurotransmitter phenotype, axonal projection and function during locomotion. [38] For example, V2 interneurons are ipsilaterally projecting that can be further classified as excitatory V2a and inhibitory V2b.