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The pinworm (species Enterobius vermicularis), also known as threadworm (in the United Kingdom, Australia and New Zealand) or seatworm, is a parasitic worm.It is a nematode (roundworm) and a common intestinal parasite or helminth, especially in humans. [7]
Hookworms are intestinal, blood-feeding, parasitic roundworms that cause types of infection known as helminthiases. Hookworm infection is found in many parts of the world, [1] and is common in areas with poor access to adequate water, sanitation, and hygiene.
Pinworm infection occurs worldwide, [10] and is the most common helminth (i.e., parasitic worm) infection in the United States and Western Europe. [18] In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among people of all ages. [ 18 ]
An infection by a helminth is known as helminthiasis, helminth infection, or intestinal worm infection. There is a naming convention which applies to all helminths: the ending "-asis" (or in veterinary science: "-osis") is added at the end of the name of the worm to denote the infection with that particular worm.
This therapy ties to the Hygiene hypothesis in that the lack of exposure to bacteria and parasites such as helminths can cause a weaker immune system leading to being more susceptible to autoimmune disease. [4] [5] Helminth worms are members of two phyla: nematodes, which are primarily used in human helminthic therapy, and flat worms . [2]
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Helminth proteins can result in a deregulated response to infection, and are implicated in reduced reactivity to other antigens. [1] Other helminth proteins promote parasite survival in other ways, particularly since parasites must depend on hosts for the supply of essential nutrients. [2]
The ways in which anthelmintics are used have contributed to a major anthelmintic resistance issue worldwide. From the 1950s to the 1980s, new classes of effective and inexpensive anthelmintics were made available every decade, leading to excessive use throughout agriculture and disincentivizing alternative anti-nematodal strategies. [ 13 ]