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JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
CB 2 (3.5x) JWH-358 [14] Dibenzopyran: 1243 ± 266: 52 ± 3: CB 2 (24x) JWH-359: Dibenzopyran: 2918 ± 450: 13.0 ± 0.2 CB 2 (220x) JWH-360 [14] Dibenzopyran: 2449 ± 606: 160 ± 8: CB 2 (15x) JWH-361 [14] Dibenzopyran: 63 ± 3: 2.7 ± 0.1: CB 2 (23x) JWH-362 [14] Dibenzopyran: 127 ± 8 34 ± 5: CB 2 (3.7x) JWH-363 [13] Naphthoylpyrrole: 245 ± ...
JWH-073, a synthetic cannabinoid, is an analgesic chemical from the naphthoylindole family that acts as a full agonist [3] at both the CB 1 and CB 2 cannabinoid receptors. It is somewhat selective for the CB 1 subtype, with affinity at this subtype approximately 5× the affinity at CB 2 . [ 4 ]
JWH-019 is an analgesic chemical from the naphthoylindole family that acts as a cannabinoid agonist at both the CB 1 and CB 2 receptors. It is the N -hexyl homolog of the more common synthetic cannabinoid compound JWH-018 .
JWH-018; THJ-018; FUB-018; NMP-7; References This page was last edited on 23 January 2023, at 11:33 (UTC). Text is available under the Creative Commons Attribution ...
FUB-JWH-018 (also known as FUB-018) is a naphthoylindole-based synthetic cannabinoid, representing a molecular hybrid of JWH-018 and AB-FUBICA or ADB-FUBICA. [1] [2]
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BIM-018 is a synthetic cannabinoid that is the benzimidazole analog of JWH-018. It is presumed to be a potent agonist of the CB 2 receptor and has been sold online as a designer drug. [1] Related benzimidazole derivatives have been reported to be highly selective agonists for the CB 2 receptor. [2]