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The virus may affect muscles on both sides of the body, but more often the paralysis is asymmetrical. [39] Any limb or combination of limbs may be affected – one leg, one arm, or both legs and both arms. Paralysis is often more severe proximally (where the limb joins the body) than distally (the fingertips and toes). [39]
English: The poliovirus affects the motor neurons of the anterior horn cells, or the ventral (front) grey matter section in the spinal column, which control movement of the trunk and limb muscles including the intercostal muscles.
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Poliovirus is, however, strictly a human pathogen, and does not naturally infect any other species (although chimpanzees and Old World monkeys can be experimentally infected). [40] The CD155 gene appears to have been subject to positive selection. [41] The protein has several domains of which domain D1 contains the polio virus binding site.
Here is what we know about polio as a disease, ... and around 5% to 10% of paralyzed patients die when their breathing muscles become immobilized. The disease mainly affects children under 5 years ...
Polio was eliminated from most parts of the world as part of a decadeslong effort by the World Health Organization and partners to wipe out the disease. Until it is gone from the planet, the virus ...
Post-polio syndrome (PPS, poliomyelitis sequelae) is a group of latent symptoms of poliomyelitis (polio), occurring in more than 80% of polio infections. The symptoms are caused by the damaging effects of the viral infection on the nervous system and typically occur 15 to 30 years after an initial acute paralytic attack.
Muscle pain. Symptoms of polio include a high temperature, extreme fatigue, headaches, vomiting, neck stiffness and muscle pain. ... It mainly affects children under the age of five, although it ...