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Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human Genome Research Institute (NHGRI), the National Cancer Institute (NCI), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). [1]
MMHCdb allows researchers to search for PDX models by such parameters as cancer site, diagnosis, genomic properties of the engrafted human tumor, and model treatment response. Fig. 3 shows the output of a search for PDX models whose engrafted tumors have amplified KRAS, the TP53 A159V mutation, a deletion of the ALB gene, and high KIT expression.
The sale of mouse animal models began in 1933 with early sales to the United States Public Health Service and The Jackson Laboratory now provides a high proportion of the mice used in biomedical research [16] In particular, the C57BL/6J strain, which is widely used and cited is maintained at The Jackson Laboratory.
The albino laboratory mouse is an iconic model organism for scientific research in a variety of fields An SCID Intermediate coat colour Kept as a pet. The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets.
A nude mouse. A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells.
In 2002, Jax Navy celebrated its 50th anniversary with a rebranding effort that included a name change to VyStar Credit Union and approval from the states of Florida and Georgia to expand its field of membership to all who lived or worked in Duval, Clay, Nassau, St. Johns or Baker counties in Florida, and Camden, Charlton, Glynn and Ware in ...
The name BALB is a portmanteau of "Bagg" and "Albino." From 1920, the progeny of the original colony were systematically inbred , sibling to sibling, for 26 generations over 15 years. During this time, the colony passed through the care of a number of scientists, including C.C. Little and E.C. MacDowell at the Carnegie Institution of Washington ...
The brewery was founded by Lawrence Fabacher in 1890 as Jackson Bohemian Brewery; its name was later changed to Jax Beer and finally Jackson Brewing Company, after Andrew Jackson and Jackson Square. It soon grew to be a prominent regional brewery and it, along with Dixie, were the only New Orleans breweries to survive Prohibition .