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  2. Avascular necrosis - Wikipedia

    en.wikipedia.org/wiki/Avascular_necrosis

    The hematopoietic cells are most sensitive to low oxygen and are the first to die after reduction or removal of the blood supply, usually within 12 hours. [2] Experimental evidence suggests that bone cells (osteocytes, osteoclasts, osteoblasts etc.) die within 12–48 hours, and that bone marrow fat cells die within 5 days. [2]

  3. Limb infarction - Wikipedia

    en.wikipedia.org/wiki/Limb_infarction

    The major tissues affected are nerves and muscles, where irreversible damage starts to occur after 4–6 hours of cessation of blood supply. [4] Skeletal muscle, the major tissue affected, is still relatively resistant to infarction compared to the heart and brain because its ability to rely on anaerobic metabolism by glycogen stored in the cells may supply the muscle tissue long enough for ...

  4. Long bone - Wikipedia

    en.wikipedia.org/wiki/Long_bone

    The long bones of the human leg comprise nearly half of adult height. The other primary skeletal component of height are the vertebrae and skull. The outside of the bone consists of a layer of connective tissue called the periosteum. Additionally, the outer shell of the long bone is compact bone, then a deeper layer of cancellous bone (spongy ...

  5. Infarction - Wikipedia

    en.wikipedia.org/wiki/Infarction

    Causes include arterial embolisms and skeletal muscle infarction as a rare complication of long standing, poorly controlled diabetes mellitus. [12] A major presentation is painful thigh or leg swelling. [12] Bone: Infarction of bone results in avascular necrosis. Without blood, the bone tissue dies and the bone collapses. [13]

  6. Sequestrum - Wikipedia

    en.wikipedia.org/wiki/Sequestrum

    An X-ray of a child's femur showing a bony sequestrum highlighted by the blue arrow. A sequestrum (plural: sequestra) is a piece of dead bone [1] that has become separated during the process of necrosis from normal or sound bone. It is a complication (sequela) of osteomyelitis. The pathological process is as follows:

  7. Medullary cavity - Wikipedia

    en.wikipedia.org/wiki/Medullary_cavity

    Located in the main shaft of a long bone (consisting mostly of compact bone), the medullary cavity has walls composed of spongy bone (cancellous bone) and is lined with a thin, vascular membrane . [1] [2] This area is involved in the formation of red blood cells and white blood cells, and the calcium supply for bird eggshells. The area has been ...

  8. Bone marrow - Wikipedia

    en.wikipedia.org/wiki/Bone_marrow

    The bone marrow produces the cellular elements of the blood, including platelets, red blood cells and white blood cells. While much information can be gleaned by testing the blood itself (drawn from a vein by phlebotomy ), it is sometimes necessary to examine the source of the blood cells in the bone marrow to obtain more information on ...

  9. Femur - Wikipedia

    en.wikipedia.org/wiki/Femur

    The femur is the largest and thickest bone in the human body. It is considered the strongest bone by some measures, though other studies suggest the temporal bone may be stronger. On average, the femur length accounts for 26.74% of a person's height, [ 4 ] a ratio found in both men and women across most ethnic groups with minimal variation.