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Chemical castration is castration via anaphrodisiac drugs, whether to reduce libido and sexual activity, to treat cancer, or otherwise. Unlike surgical castration , where the gonads are removed through an incision in the body, [ 1 ] chemical castration does not remove organs and is not a form of sterilization .
In the modern era, removing the human penis for any such activity is very rare (with some exceptions listed below), and references to removal of the penis are almost always symbolic. Castration is less rare, and is performed as a last resort in the treatment of androgen-sensitive prostate cancer. [1] [2] [3]
Castration may also refer medically to oophorectomy in female humans and animals. The term castration may also be sometimes used to refer to emasculation where both the testicles and the penis are removed together. In some cultures, and in some translations, no distinction is made between the two.
Other treatments can be started if symptoms develop, or if there are signs that the cancer growth is accelerating . [ citation needed ] Approximately one-third of men who choose active surveillance for early-stage tumors eventually have signs of tumor progression, and they may need to begin treatment within three years. [ 4 ]
Chemical castration may be preferred to surgical castration [citation needed] as it keeps the testes intact. Antiandrogen therapy; Adrenal glands were discovered as another center of androgen production even after a castration process. Therefore a complementary treatment was developed that uses antiandrogens to block the body's ability to use ...
[20] Castration or orchiectomy is a suitable option for androgen deprivation therapy, and it should be used if a very quick reduction in testosterone levels is needed. However, in recent years, orchiectomy is not commonly used since medical castration is a viable option. [ 20 ]
Castration in the genital modification and mutilation context is the removal of the testicles. Occasionally the term is also used to refer to penis removal, but that is less common. Castration has been performed in many cultures throughout history, but is now rare. It should not be confused with chemical castration.
A male student who had already performed a self-castration was the subject of a 1979 case report by Kalin. [13] [14] The student, some time after his self-castration, also attempted to reduce the activity of his adrenal glands with an injection of bovine serum albumin, luteinizing hormone-releasing hormone and Freund's adjuvant.