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Because of its antiandrogenic activity, spironolactone can cause breast tenderness, gynecomastia (breast development), feminization in general, and demasculinization, as well as sexual dysfunction including loss of libido and erectile dysfunction, although these side effects are usually confined to high doses of spironolactone. [109]
[28] [16] In addition, the AR antagonism of spironolactone is involved in its feminizing side effects, such as gynecomastia in men. [28] Spironolactone has been found to produce gynecomastia without changes in testosterone or estradiol levels, implicating AR antagonism in this side effect. [30] Gynecomastia is a major known side effect of AR ...
Eplerenone may have a lower incidence than spironolactone of sexual side effects such as feminization, gynecomastia, impotence, low sex drive and reduction of size of male genitalia. [18] This is because other antimineralocorticoids have structural elements of the progesterone molecule, causing progestogenic and antiandrogenic outcomes. [4]
Sexual side effects. Some antidepressants, including commonly prescribed ones from the class known as SSRIs (selective serotonin reuptake inhibitors), can cause sexual side effects such as ...
They are not as effective as GnRH agonists and have more side effects. [53] Antiandrogens: Bicalutamide has been used as an alternative puberty blocker in transgender girls for whom GnRH agonists were denied by insurance. [56] [57] The antiandrogens spironolactone and cyproterone acetate are not as strong. [57]
Ozempic has been linked to a host of unfortunate side effects from personality changes to weight gain after getting off the medication. Now, male users of the ever-popular weight loss remedy are ...
When used on males, these drugs can reduce sex drive, sexual fantasies, and capacity for sexual arousal. Life-threatening side effects are rare, but some users show increases in body fat and reduced bone density, which increase long-term risk of cardiovascular disease and osteoporosis, respectively.
Bupropion sexual side effects may, in other words, be benefits — like an increased sex drive. The Wellbutrin and sex drive relationship hasn’t been deeply studied, but some limited studies ...