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With an increase in the waist to hip ratio and overall waist circumference the risk of death increases as well. [7] Metabolic syndrome is associated with abdominal obesity, blood lipid disorders, inflammation, insulin resistance, type 2 diabetes, and an increased risk of developing cardiovascular disease.
Rarely, people with the hepatitis A virus can rapidly develop liver failure, termed fulminant hepatic failure, especially the elderly and those who had a pre-existing liver disease, especially hepatitis C. [17] [81] Mortality risk factors include greater age and chronic hepatitis C. [17] In these cases, more aggressive supportive therapy and ...
Wine and whole-grained bread may decrease the risk of gallstones. [26] Rapid weight loss increases risk of gallstones. [27] The weight loss drug orlistat is known to increase the risk of gallstones. [28] Cholecystokinin deficiency caused by celiac disease increases risk of gallstone formation, especially when diagnosis of celiac disease is ...
In epidemiology, a risk factor or determinant is a variable associated with an increased risk of disease or infection. [ 1 ] : 38 Due to a lack of harmonization across disciplines, determinant , in its more widely accepted scientific meaning , is often used as a synonym.
It is, however, a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. [ 2 ] [ 3 ] [ 4 ] [ 12 ] Hypertension is a major cause of premature death worldwide.
People with rheumatologic disorders such as rheumatoid arthritis, [63] ankylosing spondylitis, [63] systemic lupus erythematosus and polyarticular juvenile idiopathic arthritis are at increased risk of osteoporosis, either as part of their disease or because of other risk factors (notably corticosteroid therapy).
Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types and is driven by elevated levels of cholesterol in the blood. [9]
Being female is the single greatest risk factor for developing autoimmune disease than any other genetic or environmental risk factor yet discovered. [ 23 ] [ 24 ] Autoimmune conditions overrepresented in women include: lupus , primary biliary cholangitis , Graves' disease , Hashimoto's thyroiditis , and multiple sclerosis , among many others.