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2. 5-HT receptor - Wikipedia

   en.wikipedia.org/wiki/5-HT_receptor

   The 5-HT 1B receptor as an example of a metabotropic serotonin receptor. Its crystallographic structure in ribbon representation. 5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.

3. 5-HT3 receptor - Wikipedia

   en.wikipedia.org/wiki/5-HT3_receptor

   However, with the discovery that the 5-HT 3 receptor plays a prominent role in chemotherapy- and radiotherapy-induced vomiting, and the concomitant development of selective 5-HT 3 receptor antagonists to suppress these side effects aroused intense interest from the pharmaceutical industry [2] [33] and therefore the identification of 5-HT 3 ...

4. Serotonin–norepinephrine–dopamine reuptake inhibitor

   en.wikipedia.org/wiki/Serotonin–norepinephrine...

   In mammals, substantial concentrations of 5-HT are present in the central and peripheral nervous systems, gastrointestinal tract and cardiovascular system. 5-HT is capable of exerting a wide variety of biological effects by interacting with specific membrane-bound receptors, and at least 13 distinct 5-HT receptor subtypes have been cloned and ...

5. 5-HT1B receptor - Wikipedia

   en.wikipedia.org/wiki/5-HT1B_receptor

   3351 15551 Ensembl ENSG00000135312 ENSMUSG00000049511 UniProt P28222 P28334 RefSeq (mRNA) NM_000863 NM_010482 RefSeq (protein) NP_000854 NP_034612 Location (UCSC) Chr 6: 77.46 – 77.46 Mb Chr 9: 81.51 – 81.52 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse 5-hydroxytryptamine receptor 1B also known as the 5-HT 1B receptor is a protein that in humans is encoded by the HTR1B gene ...

6. 5-HT1A receptor - Wikipedia

   en.wikipedia.org/wiki/5-HT1A_receptor

   15550 Ensembl ENSG00000178394 ENSMUSG00000021721 UniProt P08908 Q64264 RefSeq (mRNA) NM_000524 NM_008308 RefSeq (protein) NP_000515 NP_032334 Location (UCSC) Chr 5: 63.96 – 63.96 Mb Chr 13: 105.58 – 105.58 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The serotonin 1A receptor (or 5-HT 1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin ...

7. 5-HT2C receptor agonist - Wikipedia

   en.wikipedia.org/wiki/5-HT2c_receptor_agonist

   A schematic representation of the two state-model in which the 5-HT 2C receptor are in equilibrium between an active state (R*) and an inactive state (R). 5-HT 2 receptors are G protein-coupled receptors that can regulate cellular signaling in the absence of a ligand. This can be explained by a two-state model (Figure 2) where the receptor is ...