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In normal skin, low-molecular weight hyaluronate (5 kDa) enhanced penetration into the epidermis. [17] Transepidermal water loss increased by 55.5% with low-molecular weight, and was reduced by 28% with crosslinked resilient, and by 16% with HMW. [18] Its efficacy against wrinkles has not been tested in clinical trials. [19]
A systematic review of the medical literature comparing treatments for ringworm and jock itch was generally critical of the quality of data available. It concluded that there was "insufficient evidence to determine if Whitfield's ointment, a widely used agent, is effective", [ 6 ] implying that the studies were of poor quality and therefore ...
Topical steroids are the topical forms of corticosteroids.Topical steroids are the most commonly prescribed topical medications for the treatment of rash and eczema.Topical steroids have anti-inflammatory properties and are classified based on their skin vasoconstrictive abilities. [1]
Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. It is applied as a topical cream, ointment, lotion or gel (Diprolene) to treat itching and other skin conditions such as eczema.
Sodium oxybate is rapidly absorbed with high bioavailability, however due to a very high rate of first-pass metabolism the effective bioavailability is only about 25%. [33] Less than 1% is bound to plasma protein. The average time to peak plasma concentration ranges from 0.5 to 1.25 hours. [33] It has a very short half-life of between 20 - 40 ...
Sodium tetradecyl sulfate (STS), also known by its INCI name, sodium myristyl sulfate, is a common anionic surfactant. The compound consists of the sodium salt of the micelle-forming sulfate ester of tetradecanol. It is a white, water-soluble solid of low toxicity with many practical uses. [1]
Imiquimod is a patient-applied cream prescribed to treat genital warts, Bowens disease (squamous cell carcinoma in situ), and, secondary to surgery, for basal cell carcinoma, [7] [8] as well as actinic keratosis. [9] Imiquimod 5% cream is indicated for the topical treatment of: external genital and perianal warts (condylomata acuminata) in ...
Saline solution for irrigation. Normal saline (NSS, NS or N/S) is the commonly used phrase for a solution of 0.90% w/v of NaCl, 308 mOsm/L or 9.0 g per liter. Less commonly, this solution is referred to as physiological saline or isotonic saline (because it is approximately isotonic to blood serum, which makes it a physiologically normal solution).