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2. Inverted microscope - Wikipedia

   en.wikipedia.org/wiki/Inverted_microscope

   Inverted microscopes are useful for observing living cells or organisms at the bottom of a large container (e.g., a tissue culture flask) under more natural conditions than on a glass slide, as is the case with a conventional microscope. An inverted microscope is also used for visualisation of the Mycobacterium tuberculosis bacteria in the ...

3. Live-cell imaging - Wikipedia

   en.wikipedia.org/wiki/Live-cell_imaging

   To keep cells alive during observation, the microscopes are commonly enclosed in a micro cell incubator (the transparent box). Live-cell imaging is the study of living cells using time-lapse microscopy. It is used by scientists to obtain a better understanding of biological function through the study of cellular dynamics. [1] Live-cell imaging ...

4. Leonard Hayflick - Wikipedia

   en.wikipedia.org/wiki/Leonard_Hayflick

   In 1959, Hayflick developed the first inverted microscope for use in cell culture research. To this day, all inverted microscopes used in cell culture laboratories worldwide are descended from this prototype. His microscope was accessioned by the Smithsonian Institution in 2009. Hayflick developed the first practical method for producing ...

5. Microscopy - Wikipedia

   en.wikipedia.org/wiki/Microscopy

   The use of oblique (from the side) illumination gives the image a three-dimensional appearance and can highlight otherwise invisible features. A more recent technique based on this method is Hoffmann's modulation contrast, a system found on inverted microscopes for use in cell culture. Oblique illumination enhances contrast even in clear ...

6. Prior Scientific - Wikipedia

   en.wikipedia.org/wiki/Prior_Scientific

   The Science Master Microscope, introduced in 1957, was used in schools. The established Prior Monocular Dissecting Microscope was supplied for educational use. [4] For the Imperial Cancer Research Fund in London, 1962, Prior supplied a Modular Inverted Microscope housed in a temperature controlled cabinet for cell culture examination. The ...

7. Cell culture - Wikipedia

   en.wikipedia.org/wiki/Cell_culture

   Cell culture is a fundamental component of tissue culture and tissue engineering, as it establishes the basics of growing and maintaining cells in vitro. The major application of human cell culture is in stem cell industry, where mesenchymal stem cells can be cultured and cryopreserved for future use. Tissue engineering potentially offers ...