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It is native and endemic to Madagascar, but is grown elsewhere as an ornamental and medicinal plant, and now has a pantropical distribution. It is a source of the drugs vincristine and vinblastine, used to treat cancer. [3] It was formerly included in the genus Vinca as Vinca rosea.
The Madagascan periwinkle Catharanthus roseus L. is the source for a number of important natural products, [1] including catharanthine and vindoline [2] and the vinca alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine [3] and vincristine, [4] all of which can be obtained from the plant.
Vinca alkaloids were originally manufactured by extracting them from Catharanthus roseus (Madagascar Periwinkle). [1] Podophyllum spp. Two chemotherapy drugs, etoposide and teniposide, are synthetic chemical compounds similar in chemical structure to the toxin podophyllotoxin which is found in Podophyllum peltatum (May Apple). [1] Taxus brevifolia
There are eight known species. Seven are endemic to Madagascar, [4] though one, C. roseus, is widely naturalized around the world. [2] [5] The eighth species, C. pusillus, is native to India and Sri Lanka. [6] The name Catharanthus comes from the Greek for "pure flower". [7] These are perennial herbs with oppositely or almost oppositely ...
The plant is a congeneric of the Madagascar periwinkle (C. roseus), the original main source of vinca alkaloids, also known as catharanthus alkaloids, which are still in use today as anticancer drugs. C. trichophyllus contains lower concentrations of such alkaloids. The two species can be hybridized to increase the concentration. [2]
The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...
Yohimbine should not be confused with yohimbe [4] but often is. [5]Yohimbe is the common English name for the tree species P. johimbe (also called Corynanthe johimbe) and, by extension, the name of a medicinal preparation made from the bark of that tree, sold as an aphrodisiac. [6]
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