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Photo showing the classic finding of proptosis and lid retraction in Graves' disease. Graves' ophthalmopathy is characterized by inflammation of the extraocular muscles, orbital fat and connective tissue. It results in the following signs, which can be extremely distressing to the patient: [4]
Class 0: No signs or symptoms; Class 1: Only signs (limited to upper lid retraction and stare, with or without lid lag) Class 2: Soft tissue involvement (oedema of conjunctivae and lids, conjunctival injection, etc.) Class 3: Proptosis; Class 4: Extraocular muscle involvement (usually with diplopia)
In mild disease, patients present with eyelid retraction. In fact, upper eyelid retraction is the most common ocular sign of Graves' orbitopathy. This finding is associated with lid lag on infraduction (Von Graefe's sign), eye globe lag on supraduction (Kocher's sign), a widened palpebral fissure during fixation (Dalrymple's sign) and an incapacity of closing the eyelids completely ...
What causes lower left abdominal pain? Lower left abdominal pain can have many causes, ranging from minor to serious, says Andrew Boxer, M.D., gastroenterologist of Gastroenterology Associates of ...
The condition exists in all degrees of severity and may not give rise to any adverse symptoms. Generally, however, there may be loss of appetite, heartburn, nervous indigestion, constipation, diarrhea, abdominal distention, headache, vertigo, emaciation, and loss of sleep. Any or all of these symptoms may be present.
Exophthalmos (also called exophthalmus, exophthalmia, proptosis, or exorbitism) is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor). Complete or partial dislocation from the orbit is also possible from trauma or ...
It is a dynamic sign, whereas lid lag is a static sign which may also be present in cicatricial eyelid retraction or congenital ptosis. A pseudo Graefe's sign (pseudo lid lag) shows a similar lag, but is due to aberrant regeneration of fibres of the oculomotor nerve (III) into the elevator of the upper lid. [2] It occurs in paramyotonia ...
lid lag of the lower eyelid on upward eye movement Grisel's syndrome: Pierre Grisel: rheumatology: non-traumatic subluxation of the atlanto-axial joint caused by inflammation of the adjacent tissues Gunn's sign: Robert Marcus Gunn: ophthalmology: hypertension: Gunn's sign at Whonamedit? AV "nicking" or "nipping" in hypertensive retinopathy ...