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Monocytes are a type of leukocyte or white blood cell. They are the largest type of leukocyte in blood and can differentiate into macrophages and monocyte-derived dendritic cells. As a part of the vertebrate innate immune system monocytes also influence adaptive immune responses and exert tissue repair functions.
Monocyte: Macrophage: Tissue macrophage; Macrophagocytus immobilis; 20-21 Spent neutrophils; General macrophage targets [10] [8] Kupffer cell: Monocyte: Macrophage: Stellate macrophages; Kupffer–Browicz cells; Liver macrophage; Macrophagocytus stellatus; 20-21 Foreign debris; General macrophage targets [11] [8] Alveolar macrophage: Monocyte ...
The two types of agranulocytes in the blood circulation are lymphocytes and monocytes. These make up about 35% of the hematologic blood values. [2] The distinction between granulocytes and agranulocytes is not useful for several reasons. First, monocytes contain granules, which tend to be fine and weakly stained (see monocyte entry). Second ...
The monocyte is formed in the bone marrow and transported by the blood; it migrates into the tissues, where it transforms into a histiocyte or a macrophage. Macrophages are diffusely scattered in the connective tissue and in liver (Kupffer cells), spleen and lymph nodes (sinus histiocytes), lungs (alveolar macrophages), and central nervous ...
Organ of Corti interdental epithelial cell (secreting tectorial membrane covering hair cells) Loose connective tissue fibroblasts: Corneal fibroblasts (corneal keratocytes) Tendon fibroblasts: Bone marrow reticular tissue fibroblasts: Other nonepithelial fibroblasts: Hepatic stellate cell (Ito cell) liver Pericyte: Nucleus pulposus cell ...
Leukocyte extravasation describes monocyte entry into damaged tissue through the endothelium of blood vessels as they become macrophages. Monocytes are attracted to a damaged site by chemical substances through chemotaxis, triggered by a range of stimuli including damaged cells, pathogens and cytokines released
Monocytes form two groups: a circulating group and a marginal group that remain in other tissues (approximately 70% are in the marginal group). Most monocytes leave the blood stream after 20–40 hours to travel to tissues and organs and in doing so transform into macrophages [70] or dendritic cells depending on the signals they receive. [71]
The monoblast is the first stage of monocyte-macrophage maturation. The developmental stages of the monoblast are: CFU-GM (pluripotential hemopoietic stem cell or hemocytoblast) -> monoblast -> promonocyte-> monocyte-> macrophage/dendritic cell. During their development, monocytes are present in large packs in all of the lymph nodes in the body ...