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Face wash, face moisturizer, SPF, an antioxidant serum for daytime and an AHA or retinol serum for evening are non-negotiables, then comes a growth factor serum, explains Dr. Rogers.
Dermatologists explain growth factor serums, recommend the best ones for youthful-looking skin, and explain the benefits of the anti-aging skincare ingredients.
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Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene. [5] As a member of the epidermal growth factor (EGF) family, TGF-α is a mitogenic polypeptide. [6] The protein becomes activated when binding to receptors capable of protein kinase activity for cellular signaling.
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-k Da [ 5 ] and has 53 amino acid residues and three intramolecular disulfide bonds .
The keratinocyte growth factor (KGF), also known as FGF7, is a growth factor present in the epithelialization-phase of wound healing. In this phase, keratinocytes are covering the wound, forming the epithelium. KGF is a small signaling molecule that binds to fibroblast growth factor receptor 2b (FGFR2b). [1]
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In cancer treatment, growth factor receptor inhibitors have been used to target cancer cells. [2]In cancer research, growth factor receptor inhibitors have been applied to protect normal cells selectively from the toxic side-effects of chemotherapy targeted against cancer cells.
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